Home / Journals / MCB / Vol.16, No.4, 2019
Table of Content
  • Open Access

    ARTICLE

    New Concept in Stroke Diagnosis

    Ali. E. Dabiri1,2,*, Richard Leigh3, Ghassan S. Kassab1
    Molecular & Cellular Biomechanics, Vol.16, No.4, pp. 225-233, 2019, DOI:10.32604/mcb.2019.07962
    Abstract Stroke is a life-threatening event that is expected to more than double over the next 40 years. Approximately 85% of strokes are ischemic in nature and result from thromboembolic occlusion of a major cerebral artery or its branches. One of the diagnostic methods for detection of the cerebral ischemia is the gadolinium-enhanced MRI imaging. It is mainly used in patients to detect brain tissue damaged by an ischemic stroke and brain hemorrhage. These techniques are expensive, require sophisticated machines and are time consuming. A recent study in acute stroke patients showed gadolinium leakage into ocular structures (GLOS) during MRI imaging… More >

  • Open Access

    ARTICLE

    Quantitative Method for Biomechanical Evaluation of Bedding Comfortableness

    Akisue Kuramoto1,*, Hitoshi Kimura2, Norio Inou2
    Molecular & Cellular Biomechanics, Vol.16, No.4, pp. 235-243, 2019, DOI:10.32604/mcb.2019.08123
    Abstract Comfortable bedding is usually designed subjectively because of the difficulty in performing a quantitative evaluation. This paper proposes a quantitative evaluation method of comfortableness of beddings. The bedding shape determining how comfortable an individual may feel in using it depends on the body shape and normal posture of individuals. The internal physical load is expected to relate to the comfortableness of bedding. However, only a few quantitative discussions exist on the relation between the comfortableness of bedding and physical load. This study proposes a new evaluation method of physical load in a relaxed posture. The strain energy of muscles and… More >

  • Open Access

    ARTICLE

    Magnetic Resonance Image-Based Modeling for Neurosurgical Interventions

    Yongqiang Li1,#, Changxin Lai1,#, Chengchen Zhang2, Alexa Singer1, Suhao Qiu1, Boming Sun2, Michael S. Sacks3, Yuan Feng1,*
    Molecular & Cellular Biomechanics, Vol.16, No.4, pp. 245-251, 2019, DOI:10.32604/mcb.2019.07441
    Abstract Surgeries such as implantation of deep brain stimulation devices require accurate placement of devices within the brain. Because placement affects performance, image guidance and robotic assistance techniques have been widely adopted. These methods require accurate prediction of brain deformation during and following implantation. In this study, a magnetic resonance (MR) image-based finite element (FE) model was proposed by using a coupled Eulerian-Lagrangian method. Anatomical accuracy was achieved by mapping image voxels directly to the volumetric mesh space. The potential utility was demonstrated by evaluating the effect of different surgical approaches on the deformation of the corpus callosum (CC) region. The… More >

  • Open Access

    ARTICLE

    Optical-CT Dual-Modality Mapping Base on DRR Registration

    Qingyang Zang1, Dongsheng Li1, Chunxiao Chen1,*, Jianfei Li1
    Molecular & Cellular Biomechanics, Vol.16, No.4, pp. 253-263, 2019, DOI:10.32604/mcb.2019.06999
    Abstract Optical-CT dual-modality imaging requires the mapping between 2D fluorescence images and 3D body surface light flux. In this paper, we proposed an optical-CT dual-modality image mapping algorithm based on the Digitally Reconstructed Radiography (DRR) registration. In the process of registration, a series of DRR images were computed from CT data using the ray casting algorithm. Then, the improved HMNI similarity strategy based on Hausdorff distance was used to complete the registration of the white-light optical images and DRR virtual images. According to the corresponding relationship obtained by the image registration and the Lambert’s cosine law based on the pin-hole imaging… More >

  • Open Access

    ARTICLE

    Ring Artifacts Reduction in CBCT: Pixels Detection and Patch Based Correction

    Haitong Zhao1, Yi Li1, Shouhua Luo1,*
    Molecular & Cellular Biomechanics, Vol.16, No.4, pp. 265-273, 2019, DOI:10.32604/mcb.2019.07381
    Abstract The ring artifacts introduced by the defective pixels with non-linear responses in the high-resolution detector, have a great impact on subsequent processing and quantitative analysis of the reconstructed images. In this paper, a multistep method is proposed to suppress the ring artifacts of micro CT images, which firstly locates the positions of the defective pixels in the sinogram, and then corrects the corresponding value in the projections. Since the defective pixels always appear as vertical stripes in the sinogram, a horizontal curve is derived by summing the pixel values along vertical direction, thus the abrupt segments related to the defective… More >

  • Open Access

    ARTICLE

    The Mechanical Characteristics of Human Endothelial Cells in Response to Single Ionizing Radiation Doses By Using Micropipette Aspiration Technique

    Alireza Mohammadkarim1, Manijhe Mokhtari-Dizaji2,*, Ali Kazemian3, Hazhir Saberi4, Mohammad Mehdi Khani5, Mohsen Bakhshandeh6
    Molecular & Cellular Biomechanics, Vol.16, No.4, pp. 275-287, 2019, DOI:10.32604/mcb.2019.06280
    Abstract The mechanical properties of living cells are known to be promising biomarkers when investigating the health and functions of the human body. Ionizing irradiation results in vascular injury due to endothelial damage. Thus, the current study objective was to evaluate the influence of continuous radiation doses on the mechanical properties of human umbilical vein endothelial cells (HUVECs), and to identify Young’s modulus (E) and viscoelastic behavior. Single-dose (0, 2, 4, 6, and 8 Gy) radiation was applied to HUVECs using a Cobalt-60 treatment machine in the current vitro irradiation study. Thereafter, a micropipette-aspiration technique was used to measure the elastic… More >

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