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• Open Access

Anisometry Anterior Cruciate Ligament Sport Injury Mechanism Study: A Finite Element Model with Optimization Method

Na Li*, Wei Wang*, Bin Ye*, Song Wu†,‡
Molecular & Cellular Biomechanics, Vol.11, No.2, pp. 87-100, 2014, DOI:10.3970/mcb.2014.011.087
Abstract ACL damage is one the most frequent causes of knee injuries and thus has long been the focus of research in biomechanics and sports medicine. Due to the anisometric geometry and functional complexity of the ACL in the knee joint, it is usually difficult to experimentally study the biomechanics of ACLs. Anatomically ACL geometry was obtained from both MR images and anatomical observations. The optimal material parameters of the ACL were obtained by using an optimization-based material identification method that minimized the differences between experimental results from ACL specimens and FE simulations. The optimal FE model simulated biomechanical responses of… More >

• Open Access

ARTICLE

Mass Transger in an Eccentric Annular Region Through Diffusion

Umadevi. B, Dinesh P.A., Indira R., Vinay. C.V
Molecular & Cellular Biomechanics, Vol.11, No.2, pp. 101-111, 2014, DOI:10.3970/mcb.2014.011.101
Abstract The mass transfer in an eccentric annular region through diffusion by taking blood as a Newtonian fluid with the investigation of oxygen transfer and drug transport to the tissue cells in an eccentric catheterized artery is studied. The region bounded by eccentric circles in x-y plane is mapped conformally to concentric circles in $$\xi -\eta$$ plane using a conformal mapping $$z = \lambda /1 - \zeta$$. The resulting governing equations are analytically solved by using transformation for the concentration. Numerical computations are carried out to understand the simultaneous~effects of absorption parameter and eccentricity on the flow. ~The observation through the… More >

• Open Access

ARTICLE

Experimental Evaluation of Fiber Orientation Based Material Properties of Skeletal Muscle in Tension

Chetan D. Kuthe, R.V. Uddanwadiker, Alankar Ramteke
Molecular & Cellular Biomechanics, Vol.11, No.2, pp. 113-128, 2014, DOI:10.3970/mcb.2014.011.113
Abstract Biomechanical researches are essential to develop new techniques to improve the clinical relevance. Skeletal muscle generates the force which results in the motion of human body, so it is essential to study the mechanical and structural properties of skeletal muscle. Many researchers have carried out mechanical study of skeletal muscle with in-vivo testing. This work aims to examine anisotropic mechanical behavior of skeletal muscle with in vitro test (tensile test). It is important to understand the mechanical and structural behavior of skeletal muscle when it is subjected to external loading; the research aims to determine the structural properties of skeletal… More >

• Open Access

ARTICLE

Fluid-Structure Interaction Analysis of Pulsatile Flow within a Layered and Stenotic Aorta

Zheng-qi Liu, Ying Liu∗,†, Tian-tian Liu, Qing-shan Yang
Molecular & Cellular Biomechanics, Vol.11, No.2, pp. 129-149, 2014, DOI:10.3970/mcb.2014.011.129
Abstract In this paper, the hemodynamic characteristics of blood flow and stress distribution in a layered and stenotic aorta are investigated. By introducing symmetrical and unsymmetrical stenosis, the influence of stenosis morphology and stenotic ratio on the coupled dynamic responses of aorta is clarified. In the analysis, the in-vivo pulsatile waveforms and fully fluid–structure interaction (FSI) between the layered elastic aorta and the blood are considered. The results show that the fluid domain is abnormal in the stenotic aorta, and the whirlpool forms at the obstructed and downstream unobstructed regions. The maximum wall shear stresses appear at the throat of the… More >