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Molecular & Cellular Biomechanics, Vol.19, No.3, pp. 115-129, 2022, DOI:10.32604/mcb.2022.022658
Abstract Research on dance lower extremity joint motion has been limited. Thus, the purpose of this study was to investigate the lower limb biomechanics differences between the side chasse step (SCS) and the bounce step (BS) of the second landing phase in Jive. Thirteen female recreational Latin dancers (Age: 22 ± 2.5 years; Height: 1.65 ± 0.05 m; Weight: 50 ± 4.5 kg; Dance experience: 4 ± 2 years) were involved in the experiment. The same music was used throughout the data collection period. We intended to determine whether these two steps generate different kinematic and kinetic data. The ankle, hip, and knee joint angle, moment, velocity, and… More >

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247

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Molecular & Cellular Biomechanics, Vol.19, No.3, pp. 131-139, 2022, DOI:10.32604/mcb.2022.019342
Abstract When basketball players play against each other in a game, better coordinated balance can give them a better advantage. This paper briefly introduces the coordination balance and core strength of basketball players. Twenty basketball varsity members were selected from Chengdu College of University of Electronic Science and Technology of China as subjects for the test. The athletes were randomly divided into a control group and an experimental group. The control group received regular strength training, and the experimental group received core strength training in addition to regular training. Both groups underwent isometric muscle strength test, coordination and balance test and… More >

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366

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280

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Molecular & Cellular Biomechanics, Vol.19, No.3, pp. 141-149, 2022, DOI:10.32604/mcb.2022.018558
Abstract This study aims to analyze the difference in biomechanical properties of football players at different levels when kicking the football with the inner edge of the instep. Before the experiment, ten football players were selected; five were higher than the national level (group A), and the other five players were lower than the national level II (group B). During the experiment, the motion process was captured by a high-speed camera for biomechanical analysis. It was found that in group A, the thigh and leg swung in less time and larger amplitude, the acceleration of backswing and forward swing of the… More >

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355

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241

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Molecular & Cellular Biomechanics, Vol.19, No.3, pp. 151-157, 2022, DOI:10.32604/mcb.2022.018578
Abstract Myopia is a common ophthalmic deficiency. The structure and function of choroid layer is assumed to be associated with myopia. In this study, a laboratory developed spectral domain optical coherence tomography scanning system is used to image human eyes. The axial resolution of the system is about 7 μm, and the acquisition rate is 100 kHz. Firstly, a cross-sectional image was acquired by averaging 100 images from imaging posterior segment of each eye. The choroid thickness was measured by 11 discrete points. The average thickness of normal human eyes was (0.296 ± 0.126) mm, whereas the average choroid thickness of… More >

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358

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244

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Molecular & Cellular Biomechanics, Vol.19, No.3, pp. 159-164, 2022, DOI:10.32604/mcb.2022.019005
Abstract Putting the thread through the eye of a needle is a very ordinary issues in daily life. The mechanism of putting the thread through the eye of a needle is quite similar to threading a series of polymer chains through synthetic macrocycle in bioscience. A new rubbing approach to thread through the eye of a needle was proposed in this paper, and its potential application in the fields of biomechanics and mechanobiology to mimic the micro scale assembly processes was discussed. More >

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240

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Molecular & Cellular Biomechanics, Vol.17, No.1, pp. 19-24, 2020, DOI:10.32604/mcb.2019.07817
Abstract Kinematic and dynamic characteristics of pulsating flow in a model of human aortic arch are obtained by a computational analysis. Three-dimensional flow processes are summarized by pressure distributions on the symmetric plane together with velocity and pressure contours on a few cross sections for systolic acceleration and deceleration. Without considering the effects of aortic tapering and the carotid arteries, the development of tubular boundary layer with centrifugal forces and pulsation are also analyzed for flow separation and backflow during systolic deceleration. More >

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Molecular & Cellular Biomechanics, Vol.17, No.1, pp. 41-48, 2020, DOI:10.32604/mcb.2019.07383
Abstract Motion artifacts of in vivo imaging, due to rapid respiration rate and respiration displacements of the mice while free-breathing, is a major challenge in micro computed tomography(micro-CT). The respiratory gating is often served for either projective images acquisition or per projection qualification, so as to eliminate the artifacts brought by in vivo motion. In this paper, we propose a novel respiratory gating method, which firstly divides one rotation cycle into a number of segments, and extracts the respiratory signal from the projective image series of current segment by the value of the epipolar consistency conditions (ECC), then in terms of… More >

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Molecular & Cellular Biomechanics, Vol.17, No.1, pp. 49-62, 2020, DOI:10.32604/mcb.2019.07534
Abstract In order to predict and evaluate injury mechanism and biomechanical response of the facial impact on head injury in a crash accident. With the combined modern medical imaging technologies, namely computed tomography (CT) and magnetic resonance imaging (MRI), both geometric and finite element (FE) models for human head-neck with detailed cranio-facial structure were developed. The cadaveric head impact tests were conducted to validate the headneck finite element model. The intracranial pressure, skull dynamic response and skull-brain relative displacement of the whole head-neck model were compared with experimental data. Nine typical cases of facial traffic accidents were simulated, with the individual… More >

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2737

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Molecular & Cellular Biomechanics, Vol.17, No.1, pp. 25-31, 2020, DOI:10.32604/mcb.2019.07310
Abstract The world-wide impact of traumatic injury and associated hemorrhage on human health and well-being is significant. Methods to manage bleeding from sites within the torso, referred to as non-compressible torso hemorrhage (NCTH), remain largely limited to the use of conventional operative techniques. The overall mortality rate of patients with NCTH is approximately 50%. Studies from the wars in Afghanistan and Iraq have suggested that up to 80% of potentially survivable patients die as a result of uncontrolled exsanguinating hemorrhage. The commercially available resuscitative endovascular balloon occlusion of the aorta (REBOA) is a percutaneous device for the rapid control of torso… More >

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2605

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Molecular & Cellular Biomechanics, Vol.17, No.1, pp. 33-40, 2020, DOI:10.32604/mcb.2019.07165
Abstract CT and MRI are often used in the diagnosis and monitoring of stroke. However, they are expensive, time-consuming, produce ionizing radiation (CT), and not suitable for continuous monitoring stroke. Microwave imaging (MI) has been extensively investigated for identifying several types of human organs, including breast, brain, lung, liver, and gastric. The authors recently developed a holographic microwave imaging (HMI) algorithm for biological object detection. However, this method has difficulty in providing accurate information on embedded small inclusions. This paper describes the feasibility of the use of a multifrequency HMI algorithm for brain stroke detection. A numerical system, including HMI data… More >

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2462

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Molecular & Cellular Biomechanics, Vol.17, No.1, pp. 1-17, 2020, DOI:10.32604/mcb.2019.07606
Abstract We present a theoretical approach to study the onset of failure localization into cracks in arterial wall. The arterial wall is a soft composite comprising hydrated ground matrix of proteoglycans reinforced by spatially dispersed elastin and collagen fibers. As any material, the arterial tissue cannot accumulate and dissipate strain energy beyond a critical value. This critical value is enforced in the constitutive theory via energy limiters. The limiters automatically bound reachable stresses and allow examining the mathematical condition of strong ellipticity. Loss of the strong ellipticity physically means inability of material to propagate superimposed waves. The waves cannot propagate because… More >

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2586

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Molecular & Cellular Biomechanics, Vol.17, No.2, pp. 93-99, 2020, DOI: 10.32604/mcb.2019.08267
Abstract Cryotherapy, or more commonly known as cold therapy, is the use of low temperatures in medical treatment. The most prominent use of cryotherapy is for cryosurgery where application of very low temperatures is used to ablate diseased tissue (e.g., most commonly in dermatology). Recent research, however, shows that low temperature may modulate collagen fibers beyond the already known effects of extreme cooling on joint pain relieve and inflammation. The goal of this brief review is to outline the known effects of extreme cooling on molecular, fiber and cell physiology and to leverage these properties in various potential medical applications. Specially,… More >

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2190

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Molecular & Cellular Biomechanics, Vol.17, No.2, pp. 85-92, 2020, DOI: 10.32604/mcb.2019.07386
Abstract Micro-CT provides a high-resolution 3D imaging of micro-architecture in a non-invasive way, which becomes a significant tool in biomedical research and preclinical applications. Due to the limited power of micro-focus X-ray tube, photon starving occurs and noise is inevitable for the projection images, resulting in the degradation of spatial resolution, contrast and image details. In this paper, we propose a C-GAN (Conditional Generative Adversarial Nets) denoising algorithm in projection domain for Micro-CT imaging. The noise statistic property is utilized directly and a novel variance loss is developed to suppress the blurry effects during denoising procedure. Conditional Generative Adversarial Networks (C-GAN)… More >

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2438

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Molecular & Cellular Biomechanics, Vol.17, No.3, pp. 113-118, 2020, DOI:10.32604/mcb.2020.09643
Abstract Fibrillar fibronectin (FFN) is a biological active form of FN which form linear and branched meshwork around cells and support cellular activities. Previous studies have demonstrated that shear stress can induce cell-free FN fibrillogenesis. In this study, we further examined the effect of shear stress conditions on morphology of formed FFN and preliminarily looked for relationship between FFN’s morphology and cell adhesion. Plasma FN at 50 µg/ml was perfused through channel slides at shear rates of 500 s^-1 or 4000 s^-1. Our results showed that there were four FFN structures formed: (1) FN nodules, (2) fibril in different sizes (3)… More >

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Molecular & Cellular Biomechanics, Vol.17, No.3, pp. 101-111, 2020, DOI:10.32604/mcb.2020.09595
Abstract Prostate cancer is the most common cancer among men beyond 50 years old, and ranked the second in mortality. The level of Prostate-specific antigen (PSA) in serum has been a routine biomarker for clinical assessment of the cancer development, which is detected mostly by antibody-based immunoassays. The proteolytic activity of PSA also has important functions. Here a genetically encoded biosensor based on fluorescence resonance energy transfer (FRET) technology was developed to measure PSA activity. In vitro assay showed that the biosensor containing a substrate peptide ‘RLSSYYSGAG’ had 400% FRET change in response to 1 µg/ml PSA within 90 min, and… More >

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2542

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Molecular & Cellular Biomechanics, Vol.16, No.3, pp. 211-223, 2019, DOI:10.32604/mcb.2019.07267
Abstract Force plays critical roles in cell adhesion and mechano-signaling, partially by regulating the dissociation rate, i.e., off-rate, of receptor-ligand bonds. However, the mechanism of such regulation still remains elusive. As a controversial topic of the field, when measuring the “off-rate vs. force” relation of the same molecular system, different dynamic force spectroscopy (DFS) assays (namely, force-clamp and force-ramp assays) often yield contradictive results. Such discrepancies hurdled our further understanding of molecular binding, and casted doubt on the existing theoretical models. In this work, we used a live-cell DFS technique, biomembrane force probe, to measure the single-bond dissociation in three receptor-ligand… More >

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856

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7

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Molecular & Cellular Biomechanics, Vol.16, No.2, pp. 123-140, 2019, DOI:10.32604/mcb.2019.06479
Abstract Neurons exhibit remarkably complex geometry in their neurite networks. So far, how materials are transported in the complex geometry for survival and function of neurons remains an unanswered question. Answering this question is fundamental to understanding the physiology and disease of neurons. Here, we have developed an isogeometric analysis (IGA) based platform for material transport simulation in neurite networks. We modeled the transport process by reaction-diffusion-transport equations and represented geometry of the networks using truncated hierarchical tricubic B-splines (THB-spline3D). We solved the Navier-Stokes equations to obtain the velocity field of material transport in the networks. We then solved the transport… More >

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1133

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6

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Molecular & Cellular Biomechanics, Vol.18, No.2, pp. 107-118, 2021, DOI:10.32604/mcb.2021.015453
Abstract Patellar tendinopathy is a clinical symptom of patellar tendons characterized by local pain in the front of the knee joint. It is common among basketball and volleyball players. Patients with patellar tendinopathy may exhibit different landing strategies during landing compared to healthy individuals. The purpose of this study was to compare the differences in lower limb joint energy dissipation (eccentric work) values for the symptomatic patellar tendinopathy (PT) athletes and no patellar tendinopathy (UPT) athletes during single-leg landing. A total of 26 (PT: 13, UPT:13) semi-professional male basketball and volleyball player’s kinetic data were collected during the landing phases. Joint… More >

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1235

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5

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Molecular & Cellular Biomechanics, Vol.16, No.1, pp. 27-39, 2019, DOI:10.32604/mcb.2019.06140
Abstract Digital subtraction angiography (DSA) is often used to evaluate the morphological and pathological changes of cerebral arteries in clinical practice. This study aims to explore the possibility of assessing cerebral hypoperfusion with DSA in patients with carotid stenosis. Thirty patients with a mild to severe stenosis on one side, and a mild stenosis on the other side of the carotid artery were recruited. Frontal, parietal, temporal and occipital lobes were chosen as regions of interest for measuring the quantitative perfusion parameters from their time-density curves (TDCs) of DSA images. The perfusion parameters were compared between the two hemispheres by using… More >

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940

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4

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Molecular & Cellular Biomechanics, Vol.16, No.2, pp. 141-151, 2019, DOI:10.32604/mcb.2019.06756
Abstract Airway hyperresponsiveness (AHR) is the cardinal character of asthma, which involves the biomechanical properties such as cell stiffness and traction force of airway smooth muscle cells (ASMCs). Therefore, these biomechanical properties comprise logical targets of therapy. β2-adrenergic agonist is currently the mainstream drug to target ASMCs in clinical practice for treating asthma. However, this drug is known for side effects such as desensitization and non-responsiveness in some patients. Therefore, it is desirable to search for new drug agents to be alternative of β2-adrenergic agonist. In this context, sanguinarine, a natural product derived from plants such as bloodroots, that has been… More >

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801

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4

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Molecular & Cellular Biomechanics, Vol.16, No.2, pp. 109-122, 2019, DOI:10.32604/mcb.2019.04706
Abstract The mechanical properties of single cells have been recently identified as the basis of an emerging approach in medical applications since they are closely related to the biological processes of cells and human health conditions. The problem in hand is how to measure mechanical properties in order to obtain them more accurately and applicably. Some of the cell’s properties such as elasticity module and adhesion have been measured before using various methods; nevertheless, comprehensive tests for two healthy and cancerous cells have not been performed simultaneously. As a Nanoscale device, AFM has been used for some biological cells, however for… More >

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826

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Molecular & Cellular Biomechanics, Vol.16, No.2, pp. 87-108, 2019, DOI:10.32604/mcb.2019.06415
Abstract The contractile behavior of smooth muscle cells (SMCs) in the aorta is an important determinant of growth, remodeling, and homeostasis. However, quantitative values of SMC basal tone have never been characterized precisely on individual SMCs. Therefore, to address this lack, we developed an in vitro technique based on Traction Force Microscopy (TFM). Aortic SMCs from a human lineage at low passages (4-7) were cultured 2 days in conditions promoting the development of their contractile apparatus and seeded on hydrogels of varying elastic modulus (1, 4, 12 and 25 kPa) with embedded fluorescent microspheres. After complete adhesion, SMCs were artificially detached… More >

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1174

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Molecular & Cellular Biomechanics, Vol.16, No.4, pp. 275-287, 2019, DOI:10.32604/mcb.2019.06280
Abstract The mechanical properties of living cells are known to be promising biomarkers when investigating the health and functions of the human body. Ionizing irradiation results in vascular injury due to endothelial damage. Thus, the current study objective was to evaluate the influence of continuous radiation doses on the mechanical properties of human umbilical vein endothelial cells (HUVECs), and to identify Young’s modulus (E) and viscoelastic behavior. Single-dose (0, 2, 4, 6, and 8 Gy) radiation was applied to HUVECs using a Cobalt-60 treatment machine in the current vitro irradiation study. Thereafter, a micropipette-aspiration technique was used to measure the elastic… More >

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874

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Molecular & Cellular Biomechanics, Vol.16, No.2, pp. 153-161, 2019, DOI:10.32604/mcb.2019.06873
Abstract Cardiovascular diseases are closely associated with deteriorating atherosclerotic plaques. Optical coherence tomography (OCT) is a recently developed intravascular imaging technique with high resolution approximately 10 microns and could provide accurate quantification of coronary plaque morphology. However, tissue segmentation of OCT images in clinic is still mainly performed manually by physicians which is time consuming and subjective. To overcome these limitations, two automatic segmentation methods for intracoronary OCT image based on support vector machine (SVM) and convolutional neural network (CNN) were performed to identify the plaque region and characterize plaque components. In vivo IVUS and OCT coronary plaque data from 5… More >

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1054

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Molecular & Cellular Biomechanics, Vol.3, No.4, pp. 225-227, 2006, DOI:10.32604/mcb.2006.003.225
Abstract This article has no abstract. More >

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596

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3