Open Access

REVIEW

Yan Li^1,2,3,#, Jimin Zhang^1,2,3,#, Xiaoyan Liu⁴, Kumar Ganesan⁵, Guixiu Shi^1,2,3
European Cytokine Network, Vol.35, No.1, pp. 1-12, 2024, DOI:10.1684/ecn.2024.0496
Abstract Primary Sjögren syndrome (pSS) is a systemic autoimmune disorder that affects various systems in the body, resulting in symptoms such as dry eyes and mouth, pain, and fatigue. Inflammation plays a critical role in pSS and its associated complications, with chronic inflammation being a common occurrence in patients with pSS. This review of the literature highlights inflammatory markers that could serve as indicators to predict disease progression in pSS. Results: Laboratory markers are frequently and significantly increased in pSS patients, including erythrocyte sedimentation rate, C-reactive protein, complement proteins, S100 proteins, cytokines (IFNs, CD40 ligand, soluble CD25, More >

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Open Access

ARTICLE

Shira Cohen Rubin^1,*, Nadav Zacks¹, Ori Wand², Ophir Freund³, Evgeni Gershman³, Anna Breslavsky², Rotem Givoli-Vilensky¹, Anat Tzurel Ferber², Natalya Bilenko^1,4, Amir Bar-Shai³
European Cytokine Network, Vol.35, No.1, pp. 13-19, 2024, DOI:10.1684/ecn.2024.0494
Abstract COVID-19 vaccination and acute infection result in cellular and humoral immune responses with various degrees of protection. While most studies have addressed the difference in humoral response between vaccination and acute infection, studies on the cellular response are scarce. We aimed to evaluate differences in immune response among vaccinated patients versus those who had recovered from COVID-19. Materials and Methods: This was a prospective study in a tertiary medical centre. The vaccinated group included health care workers, who had received a second dose of the BNT162b2 vaccine 30 days ago. The recovered group included adults… More >

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