Dynamics of serum cytokines in preeclampsia
Almagul Kurmanova1,2, Gulfairuz Urazbayeva3, Laura Kayupova2, Damilya Salimbaeva2, Nurzhamal Dzhardemalieva4
European Cytokine Network, Vol.35, No.2, pp. 21-27, 2024, DOI:10.1684/ecn.2024.0497
Abstract The aim of the present study was to evaluate the diagnostic significance of the dynamics of cytokines and growth factors during pregnancy with and without preeclampsia. The study included 168 pregnant women at risk of hypertensive disorders. The levels of biomarkers of all pregnant women were studied at 12-16 weeks, 28-30 weeks and 36-38 weeks. These included cytokines (tumour necrosis factor-α, interferon-γ, interleukin-4) and growth factors (placental growth factor, vascular endothelial growth factor). All pregnant women were divided into two groups: 124 patients with preeclampsia and 44 without preeclampsia (control group). In patients with preeclampsia,… More >