Guest Editor(s)
Dr. Qi Zhang
Email: zhang.qi@yale.edu
Affiliation: Department of Genetics, Yale School of Medicine, New Haven, United States
Homepage:
Research Interests: tumor epidemiology, cancer metabolism and nutrition, and cancer genetic and metabolic diseases
Summary
Inflammation and nutrition are closely interconnected determinants of human health, with cytokines serving as key mediators linking dietary factors, metabolism, immune responses, and disease outcomes. Nutritional imbalance, including undernutrition, obesity, micronutrient deficiencies, and unhealthy dietary patterns, can profoundly alter cytokine production and inflammatory signaling pathways. Persistent low-grade inflammation driven by dysregulated cytokine networks contributes to the development and progression of numerous chronic diseases, including metabolic syndrome, diabetes, cardiovascular disorders, chronic kidney disease, gastrointestinal diseases, and cancer.
This Special Issue aims to explore the emerging roles of cytokines at the interface of inflammation and nutrition. We welcome original research articles, reviews, and clinical studies addressing how nutrients, bioactive food compounds, dietary patterns, gut microbiota, and metabolic status influence cytokine responses and inflammatory pathways. Contributions focusing on cytokine biomarkers of nutritional status, nutrigenomics, immunometabolism, personalized nutrition, and nutrition-based anti-inflammatory interventions are particularly encouraged.
By integrating perspectives from molecular biology, nutrition science, immunology, and clinical medicine, this Special Issue will advance understanding of how nutrition regulates cytokine biology and provide new strategies for preventing and managing inflammation-related diseases.
Keywords
cytokines, inflammation, nutrition, immunometabolism, dietary patterns, obesity, gut microbiota, biomarkers, chronic disease, precision nutrition, functional foods, therapeutic interventions
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