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Biotherapeutic Agents and Innovative Theranostic Formulations: Physical-Chemical Aspects, Pharmacological and Biological Effects

Submission Deadline: 30 July 2021 (closed)

Guest Editors

Dr. Farid Menaa, Department of Oncology and Nanomedicine, California Innovations Corp., USA.

Dr. Barkat A Khan, Faculty of Pharmacy, Gomal University, Pakistan.


Stem cells (e.g. mesenchymal, “cancer stem cells”), mammalian biological molecules (e.g. genes, peptides, proteins, chemical or natural compounds) are emerging as complementary and alternative therapeutic solutions (e.g. gene and cell therapies) in the treatment of various health conditions. Inflammation, infections and superoxidation are largely involved in many pathological conditions, and conventional theranostic strategies are often limited in terms of safety and efficacy. Innovative polymer-based or nano-based formulations can modulate the cell behavior both morphologically and molecularly and can be a great alternative theranostic approach (e.g. tissue engineering, regenerative medicine). Screening (e.g. HTS, arrays) of drugs as well as the sequencing (e.g. NGS) of biologicals and pathological organisms are also crucial for enhancing the theranostics options (e.g. gene therapy).


This special issue focuses on physical characterizations, cellular, molecular, pharmacological, toxicological, and nanomedicinal aspects of biologicals, cells, chemical and natural compounds, that exert potential or confirmed theranostics activities (e.g. for therapeutic and/or diagnostic uses).


The effects of the biotheranostics agents and/or formulations may encompass anti-inflammatory, antioxidant, wound healing, anti-cancers, to anti-infectious activities (e.g. antibacterial, antifungal, antiparasitic and antiviral infections). Structure-function of the isolated biomolecules or cells with beneficial biological, immunological, pharmacological, and toxicological effects shall be highlighted by experimental (in vitro or ex-vivo) studies.


Researchers, industrials are kindly invited to submit their brightest review and/or research article for consideration in this Special Issue. Potential topics shall include but are not limited to:

● Human and animal pathologies

● Stem cells as theranostics

● Nanotheranostics and cellular effects

● Gene diagnosis and therapy

● Molecular and cellular pharmacology

● Phytotherapy

● Molecular screening and sequencing

● Signaling pathways

● Immunity and Inflammation


Gene Therapy, Cell Therapy, Stem Cells, Biotherapeutics, Innovative Theranostic Formulations, Signaling Pathways, Inflammation, Oxydative Stress, DNA Damage, Phytopharmacology, Pharmacognosy, Molecular Docking, Regenerative Medicine

Published Papers

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