Table of Content

Biomonitoring of Toxic Effects Using OMICs Markers

Submission Deadline: 31 January 2021 (closed)

Guest Editors

Dr. Hans-Uwe Dahms, Kaohsiung Medical University,

Dr. Mei-fang CHO, Southern Taiwan University of Technology and Science,


Biomarkers are measurable indicators of biological conditions at different levels of integration. Biomarkers in OMICs studies are used and evaluated to study normal biological processes, pathological processes, or pharmacological responses to a therapeutic intervention.


This special issue is focusing on the challenges toxicology is faced with in terms of regulation, effect, and mechanisms of action related to interactions of compounds, cells, organisms, and human individual and public health.


We welcome molecular biologists, chemists, physicists, and medical researchers to contribute original experimental or theoretical research articles and reviews on related topics.


Toxicology, Pharmacology, Biomarker, Bioassay, Bioindication, Biomedicine, Physiology, Bioinformatics, Chemcomputation, Modeling

Published Papers

  • Open Access


    The Potential Toxic Side Effects of Flavonoids

    BIOCELL, Vol.46, No.2, pp. 357-366, 2022, DOI:10.32604/biocell.2022.015958
    (This article belongs to this Special Issue: Biomonitoring of Toxic Effects Using OMICs Markers)
    Abstract Flavonoids are a class of phytochemical molecules abundant in many plants, fruits, vegetables, and leaves. Flavonoids possess a series of significant biological activities, including anticancer, antioxidant, antiviral, and antiinflammatory properties. They become an important source of dietary supplements and natural health products. Though many studies confirmed the safety of flavonoids, the potential toxicity of flavonoids is still a remarkable field of research to be explored. The enthusiasm for flavonoids expressed by the public has sometimes overlooked their toxicity and also consumed the flavonoids exceeding the body requirements. The current review focused on the potential toxicity of flavonoids to make the… More >

  • Open Access


    Carbon nanotubes: A review on risks assessment, mechanism of toxicity and future directives to prevent health implication

    BIOCELL, Vol.45, No.2, pp. 267-279, 2021, DOI:10.32604/biocell.2021.013409
    (This article belongs to this Special Issue: Biomonitoring of Toxic Effects Using OMICs Markers)
    Abstract Carbon nanotubes (CNTs) have tremendous applications in almost every walk of life; however, their harmful impacts on humans and the environment are not well addressed. CNTs have been used in various applications ranging from medical science to different engineering branches, to ease human life. Generally, the toxicological profile of CNTs under laboratory conditions cannot be assessed primarily in medical science due to the inconsistent availability of cytotoxic study data. CNT toxicity has been affected by many physicochemical properties (e.g., size, type of functionalization), concentration, the extent of exposure, mode of exposure, and even the solvents/medium used to dissolve/disperse CNTs for… More >

  • Open Access


    In silico assessment of human health risks caused by cyanotoxins from cyanobacteria

    BIOCELL, Vol.45, No.1, pp. 65-77, 2021, DOI:10.32604/biocell.2021.014154
    (This article belongs to this Special Issue: Biomonitoring of Toxic Effects Using OMICs Markers)
    Abstract Harmful algal blooms (HABs) that are formed by cyanobacteria have become a serious issue worldwide in recent years. Cyanobacteria can release a type of secondary metabolites called cyanotoxins into aquatic systems which may indirectly or directly provide health risks to the environment and humans. Cyanotoxins provide some of the most powerful natural poisons including potent neurotoxins, hepatotoxins, cytotoxins, and endotoxins that may result in environmental health risks, and long-term morbidity and mortality to animals and humans. In this research, we used the chemcomputational tool Molinspiration for molecular property predictions, Pred-hERG 4.2 web software for cardiac toxicity prediction, and Pred-Skin 2.0… More >

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