Guest Editors
Natalia A. Osna, Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, USA. nosna@unmc.edu
Zhijia Xia, Department of General, Visceral, and Transplant Surgery, Ludwig-Maximilians University, Germany. Zhijia.Xia@med.uni-muenchen.de
Summary
This special issue seeks to provide a comprehensive understanding of exosomes, their biogenesis, release pathways, content, and functions in various diseases, including cancer, cardiovascular diseases, obesity, sleep disorders, and neurodegenerative deficits. We have outlined the following key areas of focus:
Exosome Biogenesis, Release, and Content:
lInvestigate the mechanisms of exosome biogenesis and release pathways.
lExplore the diverse content of exosomes, including lipids, proteins, miRNAs, mRNAs, and other genetic materials.
Exosomes as Biomarkers:
Immunosuppressive Exosomes in Disease Microenvironments:
Therapeutic Strategies Targeting Exosomes:
Assess the viability of targeting exosomes as a therapeutic intervention in diseases with immunosuppressive microenvironments.
Explore innovative strategies to modulate exosome release, uptake, or cargo content for therapeutic benefits.
Keywords
Exosomes; Cancer; Biogenesis; Biomarkers; Immunology
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