Special Issues
Table of Content

Plant-Derived Natural Products: Phytochemical Diversity and Functional Properties

Submission Deadline: 31 December 2025 (closed) View: 596 Submit to Journal

Guest Editors

Dr. ELBOUZIDI Amine

Email: Amine.elbouzidi@ump.ac.ma

Affiliation: Laboratoire d’Amélioration des Productions Agricoles, Biotechnologie et Environnement (LAPABE), Faculté des Sciences, Université Mohammed Premier, Oujda, 60000, Morocco

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Research Interests: natural products research, plant biotechnology, medicinal plants, phytochemistry

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Dr. TAIBI Mohamed

Email: Mohamedtaibi9@hotmail.fr

Affiliation: Laboratoire d’Amélioration des Productions Agricoles, Biotechnologie et Environnement (LAPABE), Faculté des Sciences, Université Mohammed Premier, Oujda, 60000, Morocco

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Research Interests: plant chemistry, pharmacological activity, environmental impacts on plant metabolites,  materials science

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Prof. ASEHRAOU Abdeslam

Email: a.asehraou@ump.ac.ma

Affiliation: Laboratory of Bioresources, Biotechnology, Ethnopharmacology and Health, Faculty of Sciences, Mohammed First University, Boulevard Mohamed VI, B.P. 717, Oujda, 60000, Morocco

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Research Interests: microbiology, biotechnology, probiotics, bioactive compound development

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Summary

Natural products derived from plants represent a rich source of bioactive compounds with significant applications in health and agricultural sectors. These bioactivesincluding polyphenols, flavonoids, alkaloids, saponins, and terpenoidsplay critical roles in human health promotion and in enhancing the quality and resilience of agricultural outputs. Valorization strategies for these natural compounds are pivotal in advancing sustainable biotechnological applications and functional product development.


This Special Issue aims to highlight innovative research and comprehensive reviews focused on the extraction, biotechnological enhancement, functional characterization, and applied use of natural plant-derived products. Emphasis will be placed on multidisciplinary approaches combining phytochemistry, plant biotechnology, and applied sciences to optimize the utility of these metabolites in pharmaceutical, dietary, and crop enhancement contexts.


We welcome submissions of original research articles, reviews, and short communications addressing recent advances in the valorization of plant natural products, with a focus on both fundamental and applied aspects.


Potential topics include, but are not limited to:
·Advanced extraction and purification techniques of natural compounds
·Functional Applications of Phytochemicals in Agricultural Sectors
·Metabolic engineering and biotechnological approaches for enhanced bioactive production
·Plant-based bioactive as biostimulants and biofertilizers in agriculture
·Bioactivity-guided fractionation and metabolomic profiling
·Integration of omics tools in natural product discovery and application


Keywords

natural products, phytochemicals, plant biotechnology, agri-food valorization, secondary metabolites, biostimulants, metabolomics, extraction technologies

Published Papers


  • Open Access

    ARTICLE

    Metabolite Profiling and Skin Anti-Aging Potential of Astragalus sarcocolla: Antioxidant, Enzyme Inhibitory, and Computational Insights

    Shaimaa R. Ahmed, Omnia M. Hendawy, Sumera Qasim, Hanan Khojah, Ambreen Malik Uttra
    Phyton-International Journal of Experimental Botany, DOI:10.32604/phyton.2026.075718
    (This article belongs to the Special Issue: Plant-Derived Natural Products: Phytochemical Diversity and Functional Properties)
    Abstract The study evaluated the skin anti-aging activity of Astragalus sarcocolla leaves extract (ASE) by assessing its antioxidant and inhibitory effect activity on matrix metalloproteinase (MMP), collagenase, elastase, hyaluronidase, and tyrosinase in relation to its chemical composition. Ultra Performance Liquid Chromatography-Mass Spectrometry (UPLC-MS) identified 27 metabolites (15 flavonoids, 8 phenolic acids and their derivatives, and 4 coumarins). ASE showed strong antioxidant capacity in DPPH (IC50 value of 26.05 µg/mL) and FRAP (2433 µM FeSO4/g extract) assays. The extract inhibited MMP-1 and MMP-9 in a concentration-dependent manner and suppressed collagenase, elastase, hyaluronidase, and tyrosinase activities (IC50 = 35.038, 40.748, 61.389,… More >

    Graphic Abstract

    Metabolite Profiling and Skin Anti-Aging Potential of <i>Astragalus sarcocolla</i>: Antioxidant, Enzyme Inhibitory, and Computational Insights

  • Open Access

    ARTICLE

    Comparative Analysis of the Impact of Different Ecotypes on In Vitro Anti-Inflammatory Activity of Ethanolic Extracts of Moringa oleifera Leaves

    Mario D’Ambrosio, Elisabetta Bigagli, Lorenzo Cinci, Cecilia Brunetti, Edgardo Giordani, Francesco Ferrini, Cristina Luceri
    Phyton-International Journal of Experimental Botany, Vol.95, No.1, 2026, DOI:10.32604/phyton.2026.073250
    (This article belongs to the Special Issue: Plant-Derived Natural Products: Phytochemical Diversity and Functional Properties)
    Abstract Moringa oleifera (MO) is traditionally used to mitigate inflammatory-mediated disorders; however, the influence of ecotypic variation on its anti-inflammatory activity remains poorly understood. In this study, we compared the phytochemical composition and anti-inflammatory activity of ethanolic extracts obtained from fresh and dried leaves of four MO ecotypes (India, Paraguay, Mozambique, and Pakistan), all grown under the same outdoor conditions, as well as two commercial powders (Just Moringa and WISSA), using LPS-stimulated RAW 264.7 macrophages. Extracts from fresh leaves were 19–43% more cytotoxic than those from dried leaves, depending on the ecotype, likely due to higher cyanogenic… More >

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