Guest Editors
Ye Zeng, Sichuan University, China, ye@scu.edu.cn
Bingmei Fu, The City College of the City University of New York, USA, fu@ccny.cuny.edu
Danial Kahrizi, Tarbiat Modares University, Iran, d.kahrizi@cellmolbiol.org
Summary
Subcellular disorders have emerged as a significant concern in the development of various diseases. Within cells, there exist distinct membrane-bound organelles, such as the cytoplasm, peroxisomes, mitochondria, nucleus, Golgi apparatus, lysosomes, and endoplasmic reticulum, which play crucial roles in supporting cellular metabolism and combating destructive damage. Perturbations in the structure and function of these subcellular organelles can disrupt the intracellular signaling network, leading to pathological conditions. Furthermore, the response to DNA damage varies among different subcellular organelles, and the precise relationship and underlying mechanisms connecting subcellular organelles to human disease remain incompletely understood.
The primary objective of this special issue is to contribute to the understanding of the physiological and pathological aspects governing the regulation and dynamic interactions among diverse organelles. We cordially invite researchers to submit their original research articles and reviews, aiming to create a platform for the dissemination of recent advances in the following areas, among others:
• Regulatory mechanisms governing the actions of subcellular organelles
• Interplay between subcellular organelles and oxidative stress
• Impact of subcellular organelles on DNA damage response
• Identification of molecules and elucidation of mechanisms underlying the involvement of subcellular organelles in disease
• Therapeutic investigations employing subcellular organelles as targets for pharmacological interventions
We encourage contributors to explore these topics, fostering the exchange of knowledge and promoting further advancements in the field of subcellular organelle research.
Keywords
Cellular compartments; Oxidative stress; DNA damage; Disease
Published Papers
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