Table of Content

Neuroimmune Interactions at the Crossroads of Health and Disease

Submission Deadline: 30 April 2023 Submit to Special Issue

Guest Editors

Dr. Vijay Kumar, Department of Interdisciplinary Oncology, Stanley S. Scott Cancer Center, School of Medicine, Louisiana State University Health Science Center (LSUHSC), New Orleans, LA, USA.,

Prof. Giustino Varrassi, Paolo Procacci Foundation, Roma, Italy.


The nervous and immune system are most complicated biological systems in the human body. However, immunology is the one of the least static branches of modern biology among others, and so researchers must always keep asking what’s next. From here, neuroimmunology originates. Fever is a well-known example of neuroimmune interaction, for example endogenous cytokines (humoral immune components), including TNF-α, IL-1α, and IL-6 act locally as well as in the brain to induce neurological symptoms of fever, including appetite loss, muscular pain or bodyache, behavioral changes, and other changes that need direct neuroimmune interaction. However, further advancements in sciences have indicated neuroimmune interactions are crucial to maintain tissue and organ homeostasis, effective immune response during diverse inflammatory diseases, varying form infections to cancers. Hence, this special issue is focused on this emerging area that has much to explore in terms of maintaining homeostasis and disease pathogenesis.


We welcome authors to submit original research, review, and perspective articles focusing on, but not limited to, new findings in the following areas:

1.Neuroimmune interactions necessary to maintain homeostasis

2.Any inflammatory (immune) and neurological changes due to infection, internal changes (hormones, metabolism, microbiota, cancer), etc



5.Chronic pain

6.Other diseases affected by neuroimmune interaction


Immunity, Inflammation, Pain, Cytokines, Neurotransmitters, Neurodegeneration, Gut-Microbiota, Cancer, Neurons, Microglia, Astrocytes

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