Special Issues
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Innovative Strategies in Medicinal Plant Biotechnology: From Traditional Knowledge to Modern Applications

Submission Deadline: 31 December 2025 View: 712 Submit to Special Issue

Guest Editors

Dr. Naoufal El Hachlafi

Email: naoufal.elhachlafi@usmba.ac.ma 

Affiliation: Laboratory of Microbial Biotechnology and Bioactive Molecules, Sciences and Technologies Faculty, Sidi Mohamed Ben Abdellah University, P.O.Box -2202, Imouzzer Road Fez, Morocco

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Research Interests: bioactive compounds; medicinal plantes; ethnobotany; microbiology; pharmaceuticals; biological properties; experimental design; chemical characterization; drug discovery; food products; development of new antimicrobial agents

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Prof. Dr. Kawtar Fikri-Benbrahim

Email: kawtar.fikribenbrahim@usmba.ac.ma 

Affiliation: Laboratory of Microbial Biotechnology and Bioactive Molecules, Sciences and Technologies Faculty, Sidi Mohamed Ben Abdellah University, P.O.Box -2202, Imouzzer Road Fez, Morocco

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Research Interests: Biotechnogy; Microbiology; Essentiel oils; Medicinal plants; Ethnobotany; Pharmacology

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Summary

This special issue seeks to explore the multidimensional potential of medicinal plants by merging the ancient wisdom of traditional knowledge with the scientific advancements of biotechnology. Medicinal plants have been an integral part of traditional medicine, providing a vast reservoir of bioactive components used for treating a wide range of ailments. With advancements in biotechnology, such as genetic engineering, metabolic engineering, tissue culture, and nanotechnology, there is a growing opportunity to improve and optimize the production, accessibility, and therapeutic potential of these plant-based compounds.


The issue will focus on how biotechnological innovations can complement and enhance the traditional uses of plants in medicine, providing a bridge between ancient healing practices and the modern scientific understanding of plant-based therapeutics. The objective is to showcase how traditional knowledge can inspire novel biotechnological applications, and in turn, how biotechnology can validate and optimize these age-old remedies, creating effective, scalable, and sustainable solutions for today's health challenges.


Potential subjects for this topic include, but are not limited to:

- Ethnobotanical Investigations

- Phytochemical Profiling and Bioactive Compound Discovery

- Advanced analytical techniques, such as GC-MS, HPLC, NMR, and LC-MS

- Biotechnological Approaches for Enhancing Medicinal Plant Productivity

- Pharmacological Validation of Medicinal Plants

- Sustainable Practices in Medicinal Plant Biotechnology

- Nanotechnology in Medicinal Plant Applications

- Innovative Biotechnological Tools for Quality Control and Standardization

- Applications in Cosmeceuticals and Nutraceuticals


Keywords

Bioactive Plant Extracts; Ethnobotany; Sustainable Agriculture; Metabolic Engineering; Pharmacological Validation; Plant-Based Therapies; Plant Biotechnology

Published Papers


  • Open Access

    ARTICLE

    HPLC-DAD Profiling and Diuretic Effect of Solanum elaeagnifolium (Cav.) Aqueous Extract: A Combined Experimental and Computational Approach

    Bouslamti Mohammed, Nouioura Ghizlane, Tbatou Widad, Mohamed Chebaibi, Abdulsalam Alhalmi, Najoua Soulo, Sulaiman Mohammed Alnasser, Fahad M Alshabrmi, Amine Elbouzidi, Lyoussi Badiaa, Benjelloun Ahmed Samir
    Phyton-International Journal of Experimental Botany, Vol.94, No.5, pp. 1505-1518, 2025, DOI:10.32604/phyton.2025.063896
    (This article belongs to the Special Issue: Innovative Strategies in Medicinal Plant Biotechnology: From Traditional Knowledge to Modern Applications)
    Abstract The Solanum genus is known for its diverse bioactive compounds, yet its diuretic potential remains understudied. This research commenced with an analysis of polyphenol and flavonoid content in Solanum elaeagnifolium leaf extract (SEFE) using colorimetric techniques, followed by HPLC-DAD to delineate its chemical composition. The aqueous extract revealed prominent constituents: naringin (12.38%), quercetin 3-O-B-D-Glucoside (27.25%), and flavone (15.26%). A 15-day study on normal rats investigated the diuretic potential of SEFE at repeated doses. SEFE significantly increased urine volume and urinary sodium/potassium levels without inducing hypokalaemia, contrasting with furosemide, a standard diuretic that induced hypokalaemia. Conversely, furosemide, a… More >

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