Guest Editors
Dr. Manish Kuchakulla
Email: mrk9019@nyp.org
Affiliation: Department of Urology, Weill Cornell Medical College
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Research Interests: Metabolism, obesity, fertility, hypogonadism, spermatogenesis, lifestyle, exercise, and nutrition
Dr. Hriday Bhambhvani
Email: rox9006@nyp.org
Affiliation: Department of Urology, Weill Cornell Medical College
Homepage:
Research Interests: Metabolism, obesity, fertility, hypogonadism, spermatogenesis, lifestyle, exercise, and nutrition
Summary
Male reproductive health is increasingly recognized as a sensitive indicator of overall metabolic and lifestyle well-being. The rising prevalence of obesity, diabetes, and sedentary behaviors has paralleled declines in semen quality, testosterone levels, and fertility, underscoring the need for clinical studies that clarify these interconnections in real-world patient populations.
This Special Issue aims to explore the clinical and translational links between metabolic health, lifestyle behaviors, and male reproductive outcomes. We invite original investigations, clinical trials, and cohort studies that evaluate patient-centered interventions and outcomes relevant to fertility, sexual function, and endocrine balance. Studies providing mechanistic or translational insights with direct implications for clinical practice are also encouraged.
Suggested themes include:
• Clinical impact of obesity, metabolic syndrome, and diabetes on male fertility, sexual function, and hormonal health
• Effects of diet, exercise, pharmacologic and weight-loss therapies (including GLP-1 receptor agonists) in male reproductive or andrology clinics
• Influence of behavioral and environmental factors such as stress, sleep, and substance use on male reproductive health
• Preventive and management strategies for metabolic and reproductive health in urological and andrology practice
Together, these contributions will highlight how modifiable metabolic and lifestyle factors shape male reproductive potential and inform evidence-based clinical care.
Keywords
Metabolism, Obesity, Male infertility, Hypogonadism, Lifestyle, Exercise, Nutrition, GLP-1 agonists, Sperm quality, and Sexual function
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