Renal Ewing sarcoma with an unusual presentation: a case report

Felix Lübbersmeyer, Paula Lindfeld, Margit Fisch, Roland Dahlem, Markus Von Deimling^*
Department of Urology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
* Corresponding Author: Markus Von Deimling. Email: email

Canadian Journal of Urology https://doi.org/10.32604/cju.2026.076969

Received 30 November 2025; Accepted 28 February 2026; Published online 26 March 2026

Abstract

Backgrounds: Ewing Sarcoma (ES) is an aggressive pediatric bone tumor requiring multimodal treatment. Primary renal ES is extremely rare and often presents with nonspecific symptoms, potentially delaying diagnosis. Imaging aids detection, while histopathological and molecular analyses confirm the diagnosis. Case description: We report on a 31-year-old female who was initially treated for pyelonephritis. As computerized tomography suggested a malignant kidney tumor with an extensive inferior vena cava thrombus, nephrectomy and caval ligation were performed. Histopathology and further staging confirmed primary renal ES, which was subsequently treated with adjuvant polychemotherapy. Conclusions: The present case highlights the variable clinical spectrum of malignant kidney tumors. ES should be considered in the differential diagnosis of atypical renal masses.