Special Issues
Table of Content

Advances in Diagnosis and Management of Bladder Cancer: From Molecular Insights to Therapeutic Innovations

Submission Deadline: 31 July 2026 View: 82 Submit to Special Issue

Guest Editors

Dr. Ali BOURGI

Email: a.bourgi@chu-tours.fr

Affiliation: Department of Urology, University Hospital of Tours, 37044 Tours, France

Homepage:

Research Interests: Bladder cancer, urothelial carcinoma, health data analysis, treatment pathways, immunotherapy, biomarkers

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Summary

Bladder cancer remains one of the most challenging urological malignancies due to its high recurrence rate, therapeutic complexity, and molecular heterogeneity. With the advent of novel molecular diagnostics, immunotherapies, and risk stratification tools, the clinical landscape of bladder cancer management is rapidly evolving. This Special Issue aims to bring together cutting-edge research and expert reviews addressing the full spectrum of bladder cancer care—from early detection and epidemiology to biomarkers, surgical advances, systemic therapies, and survivorship.

The Special Issue will serve as a comprehensive platform for discussing translational and clinical breakthroughs, highlighting multidisciplinary approaches and innovations. Particular attention will be paid to personalized medicine, integration of omics technologies, the role of microbiome and immunotherapy, and real-world data on treatment pathways.

Suggested Themes
· Epidemiology and prevention of bladder cancer
· Molecular classification and biomarkers
· Role of DNA damage response in therapy
· Surgical innovations and robotic approaches
· BCG treatment strategies and alternatives
· Immunotherapy and checkpoint inhibitors
· Microbiome and tumor immunity
· Real-world evidence and SNDS/claims-based analyses
· Survivorship and quality of life

We invite researchers and clinicians from diverse disciplines—including urologic oncology, medical and radiation oncology, molecular biology, and health policy—to contribute to this Special Issue. By combining expertise across these fields, we aim to accelerate the translation of research findings into clinical practice and ultimately enhance outcomes and quality of care for patients with bladder and prostate cancers.


Keywords

Bladder cancer, urothelial carcinoma, immunotherapy, biomarkers, molecular classification, SNDS, epidemiology, microbiome, surgery

Published Papers


  • Open Access

    ARTICLE

    Uretero-enteric strictures after cystectomy: revealing the modifiable risk factors

    Abdelkader Akkad, Franck Bruyere, Ali Bourgi
    Canadian Journal of Urology, DOI:10.32604/cju.2025.069546
    (This article belongs to the Special Issue: Advances in Diagnosis and Management of Bladder Cancer: From Molecular Insights to Therapeutic Innovations)
    Abstract Objectives: Uretero-enteric strictures are feared complications following cystectomy. Despite surgical advancements, particularly the rise of robot-assisted approaches, the risk factors associated with these strictures remain poorly defined. This study aimed to identify the risk factors associated with uretero-enteric anastomotic strictures after cystectomy, according to the surgical approach and type of urinary diversion (extracorporeal vs. intracorporeal). Methods: We conducted a single-center retrospective study including 340 patients who underwent cystectomy between 2016 and 2024 at Tours University Hospital. Clinical, biological, perioperative, and postoperative data were analyzed. The occurrence of a uretero-ileal anastomotic stricture was defined radiologically by… More >

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