Guest Editors
Dr Liang He
Email: lianghe9278@jlu.edu.cn
Affiliation: Department of Urology, First Hospital of Jilin University, China
Homepage:
Research Interests: Clinical management of rare and complex urologic conditions, translational approaches integrating imaging, pathology, biomaterials for improved diagnosis and treatment planning in urology fields.

Summary
The management of complex and rare urologic diseases—including uncommon tumors, congenital anomalies, severe infections, and complications from reconstructive surgery—remains a significant clinical challenge. These conditions are often characterized by heterogeneous molecular profiles, variable clinical courses, and unpredictable responses to conventional treatments. Traditional diagnostic and therapeutic approaches frequently fall short, leading to delayed diagnoses, suboptimal outcomes, and increased patient morbidity.
Recent advances in genomics, molecular diagnostics, and targeted therapies have opened new avenues for precision medicine, allowing for more individualized approaches to patient care. However, knowledge gaps persist regarding disease mechanisms, optimal treatment strategies, and the integration of emerging technologies into routine clinical practice. Multidisciplinary collaboration and innovative research are essential to improve prognostic accuracy, therapeutic efficacy, and overall patient outcomes.
Suggested Themes but not limited:
- Clinical management strategies for rare or complex urologic diseases
- Minimally invasive and robotic surgical techniques in reconstruction and oncology
- Molecular profiling, biomarker discovery, and translational targets
- Advanced imaging and diagnostic innovations
- Multicenter registries, prospective cohort studies, and outcome evaluations
- Case-based discussions highlighting clinical challenges and solutions
- Molecularly guided therapeutics, including targeted and immunotherapies
We welcome original research, clinical studies, reviews, technical notes, and expert commentaries that provide multicenter, translational, or real-world insights, aiming to guide safe, effective, and personalized management of complex urologic diseases.
Keywords
Complex urologic diseases, diagnostic imaging, minimally invasive surgery, robotic urologic surgery, translational urology, precision medicine, molecular mechanisms.