Guest Editors
Prof. Dr. Artur Wdowiak
Email: wdowiakartur@gmail.com
Affiliation: Department of Obstetrics and Gynecology, Medical University of Lublin,
Staszica 16, 20-081 Lublin, Poland
Homepage:
Research Interests: andrology, infertility
Summary
Male infertility is an increasingly prevalent global health issue, affecting approximately one in five couples of reproductive age. A substantial proportion of infertility cases are attributed to male factors, and mounting scientific evidence has confirmed a continuous decline in semen quality over recent decades. Despite its clinical and social significance, male infertility remains insufficiently explored in terms of underlying mechanisms, diagnostic pathways, and treatment strategies.
Health-related, genetic, epigenetic, and environmental factors all play crucial roles in male reproductive capacity. Lifestyle habits, comorbid health conditions, exposure to environmental toxins, and genetic abnormalities may impair spermatogenesis and reduce fertility potential. Comprehensive diagnostic evaluation and individualized treatment are essential, and in cases where standard therapies are ineffective, assisted reproductive technologies (ART) such as in vitro fertilization (IVF) are employed. Importantly, interdisciplinary collaboration between urologists and gynecologists is critical for optimizing outcomes.
This Special Issue titled "Health Determinants of Male Fertility" aims to address the multifactorial nature of male reproductive disorders by integrating clinical insights with advances in basic science. The issue will emphasize the biological, clinical, and environmental determinants of male fertility, and encourage the development of improved diagnostic tools, evidence-based interventions, and preventive strategies.
Suggested Themes (but not limited to):
- Health and Systemic Conditions in Male Infertility: The impact of metabolic disorders, endocrine imbalances, and chronic diseases.
- Genetic and Epigenetic Factors: The role of chromosomal abnormalities, gene expression, and epigenetic modifications in male fertility.
- Environmental and Lifestyle Influences: Effects of pollution, occupational exposures, diet, smoking, and stress.
- Diagnostics in Male Infertility: Advances in semen analysis, imaging, hormonal assessment, and molecular biomarkers.
- Clinical Management and Treatment Strategies: Pharmacological therapies, surgical interventions, and ART approaches.
- Interdisciplinary Collaboration in Fertility Care: Integration of urology, andrology, and gynecology in patient management.
- Public Health Perspectives: The societal and demographic implications of declining male fertility.
This Special Issue invites original research articles, systematic reviews, meta-analyses, and clinical studies that contribute to a comprehensive understanding of male fertility determinants. By fostering collaboration between clinical and research disciplines, this issue aims to advance both the scientific knowledge and clinical management of male infertility, ultimately improving reproductive outcomes and patient care.
Keywords
semen, infertility, semen analysis, genetic factors, epigenetic factors, environmental factors,reproductive health .
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