Guest Editors
Prof. Dr. Tiago Rodrigues
Email: tiagorodrigues@gupuro.pt
Affiliation: Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, Avenida Professor Gama Pinto 1649-003, Lisbon, Portugal
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Research Interests: Uro-oncology, robotic surgery, non-radical prostate cancer treatment, micro-ultrasound, HIFU, BPH
Prof. Dr. James S. Wysock
Email: james.wysock@nyulangone.org
Affiliation: Department of Urology, NYU Grossman School of Medicine, New York, NY, USA
Homepage:
Research Interests: urologic oncology, cancers of the kidneys, ureters, bladder, prostate, and testes, MRI-US fusion biopsy
Summary
The management of localized prostate cancer is transitioning toward non‑radical, organ‑preserving treatments, driven by advances in precision diagnostics and minimally invasive technologies. While prostatectomy and radiotherapy remain standard, their risk of urinary and sexual dysfunction has spurred interest in focal therapies that aim to maintain oncologic efficacy and improve quality of life.
This Special Issue highlights these emerging approaches—including HIFU, cryoablation, laser ablation, micro‑ultrasound, and robotic guidance—and covers key areas such as patient selection, imaging-guided therapy, post-treatment follow-up, and patient-centered outcomes. We invite original research, clinical studies, technical notes, and expert reviews that provide robust, multicenter, and international insights.
Our goal is to compile an authoritative reference guiding the safe, effective, and personalized implementation of non‑radical treatment in routine urologic practice, laying groundwork for future consensus and guideline development.
Suggested Themes
· Patient selection & risk stratification beyond ISUP (e.g., tumor volume, genomics)
· Prostate imaging & biopsy innovations (mpMRI, micro-ultrasound, PRIMUS)
· Robotic & non‑invasive focal therapies (HIFU, cryoablation, laser ablation)
· Follow‑up protocols & imaging surveillance strategies
· Outcome measures & patient‑reported quality of life
· International, multicenter, real-world case series
· Technical performance & learning curve of new focal platforms
We invite contributions spanning original research, clinical studies, systematic and narrative reviews, expert commentaries, and technical developments that illuminate the evolving role of non-radical therapy in achieving oncologic control while preserving quality of life in prostate cancer management.
Keywords
Non-radical treatment, prostate cancer, robotic HIFU, minimally invasive therapy, patient-centered care, imaging,
Published Papers
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