Guest Editors
Dr. Le Ba Vinh
Email: vinhrooney@gmail.com
Affiliation: Department of Chemistry, University of Bergen, Bergen 5007, Norway
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Research Interests: metabolomic, natural product, biochemistry, herbal medicine, bioactive compound
Dr. Pham Giang Nam
Email: nam.phamgiang@phenikaa-uni.edu.vn
Affiliation: Faculty of Pharmacy, PHENIKAA University, Yen Nghia, Ha Dong, Hanoi 12116, Vietnam
Homepage:
Research Interests: metabolomic, natural product, biochemistry, herbal medicine, bioactive compound
Summary
Natural compounds continue to serve as essential resources and sources of inspiration in drug discovery, offering a wide range of chemical diversity and biological potential. Among them, phytochemicals and structurally defined bioactive monomers derived from herbal medicine have garnered increasing attention due to their specific and well-characterized interactions with cellular targets. These compounds have been widely investigated for their therapeutic value across various disease models.
In contrast to complex extracts, individual phytochemicals exhibit a broad spectrum of pharmacological properties. These include antioxidant activity through free radical scavenging and regulation of redox-sensitive signaling pathways; anti-inflammatory effects via suppression of pro-inflammatory cytokines and inhibition of transcription factors such as NF-κB; anti-tumor and anti-cancer actions involving induction of apoptosis, inhibition of angiogenesis, and cell cycle arrest; and cardioprotective effects by modulating lipid metabolism, vascular integrity, and oxidative stress responses. These multifaceted bioactivities highlight the importance of investigating the cellular and molecular mechanisms of action of these compounds using advanced biological and analytical methods.
This Special Issue aims to gather scientific papers focusing on the chemical characterization, bioactivity profiling, and mechanistic exploration of phytochemicals and monomeric compounds from herbal medicine. We welcome submissions that apply cellular and molecular biology approaches to elucidate the pharmacological properties of these bioactive natural products. Studies integrating phytochemistry, pharmacology, and biotechnological innovation are particularly encouraged.
Keywords
herbal medicine, bioactive compound, pharmacological effect, metabolomic, anti-inflammatory effect, natural product, pharrmacosnosy
Published Papers
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