Guest Editors
Prof. Dong-Oh Moon
Email: domoon@daegu.ac.kr
Affiliation: Department of Biology Education, Daegu University, 38453 Gyeongsangbuk-do, Republic of Korea
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Research Interests: regulated cell death, immunogenic cell death, apoptosis, pyroptosis, ferroptosis, cancer immunology, natural bioactive compounds
Summary
Regulated cell death (RCD) is a fundamental biological process that maintains cellular homeostasis and orchestrates tissue development, immune responses, and disease progression. Understanding the molecular mechanisms underlying diverse RCD pathways is critical for elucidating their roles in physiology and pathology and for identifying potential therapeutic targets. This Special Issue of BIOCELL aims to gather high-quality research and review articles that advance our understanding of RCD at the cellular and molecular levels, highlighting its pathophysiological significance in health and disease.
Key areas of focus include but are not limited to:
· Molecular mechanisms and signaling pathways of classical RCD modalities, including apoptosis, ferroptosis, and pyroptosis
· Emerging and non-canonical RCD pathways such as necroptosis and autophagy-associated cell death
· Crosstalk and regulatory networks among multiple RCD pathways
· Pathophysiological roles of RCD in cancer, neurodegenerative disorders, cardiovascular diseases, infectious diseases, and immune regulation
· Identification of molecular targets and therapeutic strategies modulating RCD
· Applications of advanced technologies, including single-cell omics, molecular imaging, gene editing, and computational approaches, to study RCD mechanisms
This Special Issue seeks to provide a platform for showcasing cutting-edge research on the molecular mechanisms and pathophysiological roles of RCD, facilitating a deeper understanding of cellular homeostasis and disease progression, and promoting the translation of RCD research into novel therapeutic approaches.
Keywords
regulated cell death, apoptosis, ferroptosis, pyroptosis, necroptosis, autophagy, molecular mechanisms, pathophysiology
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