Guest Editor(s)
Prof. Dr. Vu Phong Lam
Email: phonglamdhtaybac@gmail.com
Affiliation: Department of Horticultural Science, Chungnam National University, Daejeon, Republic of Korea
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Research Interests: hydroponic system, horticulture environment, plant factory and greenhouse cultivation, HPLC Analysis, content of bioactive compounds in vegetable and medicine plants, vegetable production, plant environmental stress physiology, antioxidants

Summary
Plants are continuously exposed to a wide range of biotic and abiotic stresses that profoundly influence their growth, productivity, and quality. To survive under adverse environmental conditions, plants have evolved sophisticated metabolic regulatory networks that coordinate physiological, biochemical, and molecular responses. These metabolic adaptations not only enhance stress tolerance but also regulate the biosynthesis of valuable secondary metabolites, antioxidants, phytohormones, and other bioactive compounds with important agricultural, nutritional, and pharmaceutical applications.
This Special Issue, "Metabolic Mechanisms of Plant Responses to Stress," aims to provide a comprehensive platform for publishing high-quality original research and review articles that advance our understanding of plant metabolic responses to environmental challenges. The issue welcomes studies investigating the mechanisms underlying plant adaptation to drought, salinity, temperature extremes, nutrient imbalance, heavy metals, oxidative stress, pathogen infection, and controlled-environment cultivation systems such as plant factories and hydroponics. Particular emphasis will be placed on research integrating plant physiology, metabolism, molecular biology, biotechnology, and advanced analytical approaches to elucidate stress-response pathways and improve crop productivity and quality.
Suggested themes include plant secondary metabolism, antioxidant defense systems, photosynthesis under stress, metabolomics, transcriptomics, bioactive compound biosynthesis, stress signaling networks, controlled-environment agriculture, precision horticulture, and innovative strategies for enhancing plant resilience and sustainable crop production.
Keywords
controlled environment horticulture, precision environmental management, smart sensing and modeling, light, water, nutrient optimization