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Plant-Derived Antimicrobials: Phytochemical Defense, Plant Metabolism, and Ecological Roles

Submission Deadline: 01 May 2026 View: 561 Submit to Special Issue

Guest Editors

Dr. Olja Šovljanski

Email: oljasovljanski@uns.ac.rs

Affiliation: Department of Biotechnology, Faculty of Technology Novi Sad, University of Novi Sad, Novi Sad, 21000, Serbia

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Research Interests: plant extracts, plant endophytes, phytochemical diversity, antimicrobial agents, bio-based solution, bacterial biotechnology, predictive microbiology

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Summary

Antimicrobial resistance (AMR) presents a critical global challenge not only in clinical medicine but also in agriculture and ecological balance. Plants have evolved sophisticated biochemical defense mechanisms involving a wide array of antimicrobial phytochemicals, which play crucial roles in their physiology, metabolism, and interactions with microbial communities. This Special Issue focuses on recent advances in the study of plant-derived antimicrobial compounds from a plant science perspective.


We welcome contributions exploring the biosynthesis pathways, ecological functions, and evolutionary significance of these compounds in medicinal and horticultural plants. Emphasis will be placed on molecular mechanisms of plant defense, plant-microbe interactions, bioinformatics tools for metabolite profiling, and the adaptive roles of secondary metabolites in plant survival. Research that bridges traditional ethnobotanical knowledge with mechanistic insights into plant metabolism is particularly encouraged.


This issue aims to integrate perspectives from plant physiology, biochemistry, ecology, and systems biology to broaden our understanding of plant-based antimicrobial systems and their potential applications.


Suggested Themes:
· Biosynthesis and metabolic pathways of antimicrobial phytochemicals
· Role of secondary metabolites in plant defense and stress responses
· Ecological roles of antimicrobial compounds in plant-microbe interactions
· Genomics and transcriptomics of antimicrobial compound production
· Molecular and biochemical mechanisms of action in plant defense
· Comparative metabolomics of medicinal and horticultural plants
· Bioinformatics tools for metabolite discovery and pathway analysis
· Co-evolution of plants and pathogens: defense strategies and resistance
· Ethnobotanical insights into plant metabolism and antimicrobial roles
· Applications of plant antimicrobials in sustainable agriculture and crop protection


Original research, systematic reviews, and case studies are welcome, especially those that reveal how traditional plant knowledge intersects with modern plant science disciplines.


Keywords

antimicrobial phytochemicals, plant defense mechanisms, secondary metabolites, plant-microbe interactions, phytochemical biosynthesis, medicinal and horticultural plants, plant metabolism, ethnobotany, plant ecology, bioactive plant compounds, plant systems biology, plant biochemistry, natural defense strategies, botanical antimicrobials

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