Guest Editors
Assoc. Prof. Oksana Tuchina
Email: oktuchina@gmail.com
Affiliation: Educational and Scientific Cluster "Institute of Medicine and Life Sciences (MEDBIO)", Immanuel Kant Baltic Federal University, 236016 Kaliningrad, Russia
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Research Interests: autophagy, neuron-microglial interactions, neurogenesis, catecholamines, enriched environment
Assoc. Prof. Irina G. Shalaginova
Email: shalaginova_i@mail.ru
Affiliation: School of Life Sciences, Immanuel Kant Baltic Federal University, Kaliningrad 236041, Russia
Pavlov Institute of Physiology of the Russian Academy of Sciences, Saint Petersburg 199034, Russia
Homepage:
Research Interests: animal models, home-cage monitoring, gut-brain axis, reproducibility of biomedical research, behavioral phenotyping, biological psychiatry
Summary
The emergence and regulation of complex behaviorssuch as learning, decision-making, social interaction, and emotional processingare orchestrated by intricate cellular and molecular mechanisms. Disruptions in these biological processes are closely linked to a wide range of neurobiological and psychiatric disorders, including depression, anxiety, autism spectrum disorders, and neurodegenerative diseases. Despite extensive progress, the precise cellular underpinnings of behavior and its pathological alterations remain incompletely understood.
This special issue of BIOCELL seeks to highlight advances in the cellular and molecular understanding of behavior and its dysfunction in disease contexts. We invite original research and comprehensive reviews addressing the following subtopics:
·Molecular signaling pathways involved in behavioral control
·Neural cell-type-specific roles in emotion, motivation, and cognition
·Mechanisms of synaptic plasticity and their behavioral implications
·Cell stress, apoptosis, and neurodegeneration in behavior-linked disorders
·Neuroimmune and neuroendocrine modulation of behavioral states
·Epigenetic and transcriptional mechanisms in long-term behavioral change
·Glial contributions to neural circuit function and behavioral output
·Identification of cellular biomarkers for behavioral and neurological conditions
·Translational gaps in behavioral neuroscience: conceptual challenges and future directions
By integrating studies across molecular biology, cell biology, and behavioral neuroscience, this special issue aims to bridge the gap between cellular mechanisms and complex organismal outcomes. The goal is to foster a deeper understanding of how cells and molecules shape behavior in health and disease, and to inspire new therapeutic strategies targeting the cellular roots of neuropsychiatric conditions.
Keywords
behavioral neuroscience, molecular signaling, synaptic plasticity, neurodegeneration, glia-neuron interaction, emotional regulation, psychiatric disorders, brain circuits
Published Papers
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